Thank you for voting for “there’s a problem with the clipboard” issue. I think this refers to this error dialog: “There’s a problem with the clipboard, but you can still paste your content within this workbook."
When Excel shows this dialog after a copy (CTRL+C) action, it means that another app has a lock on the system clipboard. In this situation you can still paste within Excel. However you cannot paste to another app like Word or Outlook which uses the clipboard.
A while ago we made some improvements for Office365 users so that this error message only shows once per Excel instance. This was based on customer feedback – the design change prevents it popping up multiple successive times when the clipboard is locked. We have also considered never showing the error dialog, but there was user feedback that this message is informative and helpful in some cases.
An error occurred while saving the commentMiri commented
At first, I was encountering this issue occasionally, and I really could continue pasting within the spreadsheet. Now the problem happens every 10 to 15 minutes, and the only thing that I can do is close down Excel and reopen it. It won't allow me to continue working at all, much less copy/paste. I despise Office 365, would get rid of it in an instant if I could go back to a desktop version. This software defect causes me an incredible amount of lost time and irritation. Microsoft, if you don't fix it, some other enterprising company will fill the void with a new solution. Your customers are clearly fed up with your inability or lack of prioritization to fix this defect.